Garcia J, Hankins WG: The evolution of bitter and the acquisition of toxiphobia. Olfaction and Taste. 1975, 5: 39-45.
Google Scholar
Chandrashekar J, Mueller KL, Hoon MA, Adler E, Feng L, Guo W, Zuker CS, Ryba NJ: T2Rs function as bitter taste receptors. Cell. 2000, 100 (6): 703-711. 10.1016/S0092-8674(00)80706-0.
Article
PubMed
CAS
Google Scholar
Imai H, Suzuki N, Ishimaru Y, Sakurai T, Yin L, Pan W, Abe K, Misaka T, Hirai H: Functional diversity of bitter taste receptor TAS2R16 in primates. Biol Lett. 2012, 8 (4): 652-656. 10.1098/rsbl.2011.1251.
Article
PubMed
CAS
PubMed Central
Google Scholar
Glendinning JI: Is the bitter rejection response always adaptive?. Physiol Behav. 1994, 56 (6): 1217-1227. 10.1016/0031-9384(94)90369-7.
Article
PubMed
CAS
Google Scholar
Shi P, Zhang J: Contrasting modes of evolution between vertebrate sweet/umami receptor genes and bitter receptor genes. Mol Biol Evol. 2006, 23 (2): 292-300. 10.1093/molbev/msj028.
Article
PubMed
CAS
Google Scholar
Adler E, Hoon MA, Mueller KL, Chandrashekar J, Ryba NJ, Zuker CS: A novel family of mammalian taste receptors. Cell. 2000, 100 (6): 693-702. 10.1016/S0092-8674(00)80705-9.
Article
PubMed
CAS
Google Scholar
Go Y, Satta Y, Takenaka O, Takahata N: Lineage-specific loss of function of bitter taste receptor genes in humans and nonhuman primates. Genetics. 2005, 170 (1): 313-326. 10.1534/genetics.104.037523.
Article
PubMed
CAS
PubMed Central
Google Scholar
Bufe B, Breslin PA, Kuhn C, Reed DR, Tharp CD, Slack JP, Kim UK, Drayna D, Meyerhof W: The molecular basis of individual differences in phenylthiocarbamide and propylthiouracil bitterness perception. Curr Biol. 2005, 15 (4): 322-327. 10.1016/j.cub.2005.01.047.
Article
PubMed
CAS
PubMed Central
Google Scholar
Wooding S, Gunn H, Ramos P, Thalmann S, Xing C, Meyerhof W: Genetics and bitter taste responses to goitrin, a plant toxin found in vegetables. Chem Senses. 2010, 35 (8): 685-692. 10.1093/chemse/bjq061.
Article
PubMed
CAS
Google Scholar
Risso D, Morini G, Pagani L, Quagliariello A, Giuliani C, De Fanti S, Sazzini M, Luiselli D, Tofanelli S: Genetic signature of differential sensitivity to stevioside in the Italian population. Genes Nutr. 2014, 9 (3): 401-10.1007/s12263-014-0401-y.
Article
PubMed
PubMed Central
Google Scholar
Wooding S, Kim UK, Bamshad MJ, Larsen J, Jorde LB, Drayna D: Natural selection and molecular evolution in PTC, a bitter-taste receptor gene. Am J Hum Genet. 2004, 74 (4): 637-646. 10.1086/383092.
Article
PubMed
CAS
PubMed Central
Google Scholar
Campbell MC, Ranciaro A, Froment A, Hirbo J, Omar S, Bodo JM, Nyambo T, Lema G, Zinshteyn D, Drayna D, Breslin PA, Tishkoff SA: Evolution of functionally diverse alleles associated with PTC bitter taste sensitivity in Africa. Mol Biol Evol. 2012, 29 (4): 1141-1153. 10.1093/molbev/msr293.
Article
PubMed
CAS
PubMed Central
Google Scholar
Campbell MC, Ranciaro A, Zinshteyn D, Rawlings-Goss R, Hirbo J, Thompson S, Woldemeskel D, Froment A, Rucker JB, Omar SA, Bodo JM, Nyambo T, Belay G, Drayna D, Breslin PA, Tishkoff SA: Origin and differential selection of allelic variation at TAS2R16 associated with salicin bitter taste sensitivity in Africa. Mol Biol Evol. 2014, 31 (2): 288-302. 10.1093/molbev/mst211.
Article
PubMed
CAS
PubMed Central
Google Scholar
Balakirev ES, Ayala FJ: Pseudogenes: are they “junk” or functional DNA?. Annu Rev Genet. 2003, 37: 123-151. 10.1146/annurev.genet.37.040103.103949.
Article
PubMed
CAS
Google Scholar
Zhang Z, Gerstein M: Large-scale analysis of pseudogenes in the human genome. Curr Opin Genet Dev. 2004, 14 (4): 328-335. 10.1016/j.gde.2004.06.003.
Article
PubMed
CAS
Google Scholar
Bekpen C, Marques-Bonet T, Alkan C, Antonacci F, Leogrande MB, Ventura M, Kidd JM, Siswara P, Howard JC, Eichler EE: Death and resurrection of the human IRGM gene. PLoS Genet. 2009, 5 (3): e1000403-10.1371/journal.pgen.1000403.
Article
PubMed
PubMed Central
Google Scholar
Korrodi-Gregório L, Abrantes J, Muller T, Melo-Ferreira J, Marcus K, da Cruz e Silva QA, Fardilha M, Esteves PJ: Not so pseudo: the evolutionary history of protein phosphatase 1 regulatory subunit 2 and related pseudogenes. BMC Evol Biol. 2013, 13: 242-10.1186/1471-2148-13-242.
Article
PubMed
PubMed Central
Google Scholar
Zhang Q: Using pseudogene database to identify lineage-specific genes and pseudogenes in humans and chimpanzees. J Hered. 2014, 105 (3): 436-443. 10.1093/jhered/est097.
Article
PubMed
CAS
Google Scholar
Olson MV: When less is more: gene loss as an engine of evolutionary change. Am J Hum Genet. 1999, 64 (1): 18-23. 10.1086/302219.
Article
PubMed
CAS
PubMed Central
Google Scholar
Wang X, Grus WE, Zhang J: Gene losses during human origins. PLoS Biol. 2006, 4 (3): e52-10.1371/journal.pbio.0040052.
Article
PubMed
PubMed Central
Google Scholar
Shi P, Zhang J, Yang H, Zhang YP: Adaptive diversification of bitter taste receptor genes in Mammalian evolution. Mol Biol Evol. 2003, 20 (5): 805-814. 10.1093/molbev/msg083.
Article
PubMed
CAS
Google Scholar
Dong D, Jones G, Zhang S: Dynamic evolution of bitter taste receptor genes in vertebrates. BMC Evol Biol. 2009, 9: 12-10.1186/1471-2148-9-12.
Article
PubMed
PubMed Central
Google Scholar
Conte C, Ebeling M, Marcuz A, Nef P, Andres-Barquin PJ: Evolutionary relationships of the Tas2r receptor gene families in mouse and human. Physiol Genomics. 2003, 14 (1): 73-82.
Article
PubMed
CAS
Google Scholar
Go Y: Proceedings of the SMBE Tri-National Young InvestigatorsInvestigators’ Workshop. Lineage-specific expansions and contractions of the bitter taste receptor gene repertoire in vertebrates. Mol Biol Evol. 2005, 23 (5): 964-972. 10.1093/molbev/msj106.
Article
Google Scholar
Wang X, Thomas SD, Zhang J: Relaxation of selective constraint and loss of function in the evolution of human bitter taste receptor genes. Hum Mol Genet. 2004, 13 (21): 2671-2678. 10.1093/hmg/ddh289.
Article
PubMed
CAS
Google Scholar
Fischer A, Gilad Y, Man O, Pääbo S: Evolution of bitter taste receptors in humans and apes. Mol Biol Evol. 2005, 22 (3): 432-436. 10.1093/molbev/msi027.
Article
PubMed
CAS
Google Scholar
Abecasis GR, Auton A, Brooks LD, DePristo MA, Durbin RM, Handsaker RE, Kang HM, Marth GT, McVean GA: An integrated map of genetic variation from 1,092 human genomes. Nature. 2012, 491 (7422): 56-65. 10.1038/nature11632.
Article
PubMed
Google Scholar
1000 Genomes Browser.. [], [http://browser.1000genomes.org/index.html]
Karolchik D, Hinrichs AS, Furey TS, Roskin KM, Sugnet CW, Haussler D, Kent WJ: The UCSC Table Browser data retrieval tool. Nucleic Acids Res. 2004, 32: D493-D496. 10.1093/nar/gkh103.
Article
PubMed
CAS
PubMed Central
Google Scholar
UCSC Table Browser.. [], [http://genome.ucsc.edu/cgi-bin/hgTables]
Flicek P, Ahmed I, Amode MR, Barrell D, Beal K, Brent S, Carvalho-Silva D, Clapham P, Coates G, Fairley S, Fitzgerald S, Gil L, García-Girón C, Gordon L, Hourlier T, Hunt S, Juettemann T, Kähäri AK, Keenan S, Komorowska M, Kulesha E, Longden I, Maurel T, McLaren WM, Muffato M, Nag R, Overduin B, Pignatelli M, Pritchard B, Pritchard E, et al: Ensembl 2013.Nucleic Acids Res41(D1):D48–D55.,
Ensembl Genome Browser.. [], [http://www.ensembl.org/index.html]
Barrett JC, Fry B, Maller J, Daly MJ: Haploview: analysis and visualization of LD and haplotype maps. Bioinformatics. 2005, 21 (2): 263-265. 10.1093/bioinformatics/bth457.
Article
PubMed
CAS
Google Scholar
Bandelt HJ, Forster P, RRöhlhl A: Median-joining networks for inferring intraspecific phylogenies. Mol Biol Evol. 1999, 16 (1): 37-48. 10.1093/oxfordjournals.molbev.a026036.
Article
PubMed
CAS
Google Scholar
Purcell S, Neale B, Todd-Brown K, Thomas L, Ferreira MA, Bender D, Maller J, Sklar P, de Bakker PI, Daly MJ, Sham PC: PLINK: a tool set for whole-genome association and population-based linkage analyses. Am J Hum Genet. 2007, 81 (3): 559-575. 10.1086/519795.
Article
PubMed
CAS
PubMed Central
Google Scholar
Excoffier L, Lischer HE: Arlequin suite ver 3.5: a new series of programs to perform population genetics analyses under Linux and Windows. Mol Ecol Resour. 2010, 10 (3): 564-567. 10.1111/j.1755-0998.2010.02847.x.
Article
PubMed
Google Scholar
Edgar RC: MUSCLE: multiple sequence alignment with high accuracy and high throughput. Nucleic Acids Res. 2004, 32 (5): 1792-1797. 10.1093/nar/gkh340.
Article
PubMed
CAS
PubMed Central
Google Scholar
Tamura K, Stecher G, Peterson D, Filipski A, Kumar S: MEGA6: Molecular Evolutionary Genetics Analysis version 6.0. Mol Biol Evol. 2013, 30 (12): 2725-2729. 10.1093/molbev/mst197.
Article
PubMed
CAS
PubMed Central
Google Scholar
Librado P, Rozas J: DnaSP v5: a software for comprehensive analysis of DNA polymorphism data. Bioinformatics. 2009, 25 (11): 1451-1452. 10.1093/bioinformatics/btp187.
Article
PubMed
CAS
Google Scholar
Li H: A new test for detecting recent positive selection that is free from the confounding impacts of demography. Mol Biol Evol. 2011, 28 (1): 365-375. 10.1093/molbev/msq211.
Article
PubMed
Google Scholar
Bahlo M, Griffiths RC: Inference from gene trees in a subdivided population. Theor Popul Biol. 2000, 57 (2): 79-95. 10.1006/tpbi.1999.1447.
Article
PubMed
CAS
Google Scholar
GENETREE software.. [], [http://www.stats.ox.ac.uk/~griff/software.html]
Tajima F: Statistical method for testing the neutral mutation hypothesis by DNA polymorphism. Genetics. 1989, 123 (3): 585-595.
PubMed
CAS
PubMed Central
Google Scholar
Fu YX, Li WH: Statistical tests of neutrality of mutations. Genetics. 1993, 133 (3): 693-709.
PubMed
CAS
PubMed Central
Google Scholar
Schierup MH, Charlesworth D, Vekemans X: The effect of hitch-hiking on genes linked to a balanced polymorphism in a subdivided population. Genet Res. 2000, 76 (1): 63-73. 10.1017/S0016672300004547.
Article
PubMed
CAS
Google Scholar
Navarro A, Barton NH: The effects of multilocus balancing selection on neutral variability. Genetics. 2002, 161 (2): 849-863.
PubMed
PubMed Central
Google Scholar
Weir BS, Cardon LR, Anderson AD, Nielsen DM, Hill WG: Measures of human population structure show heterogeneity among genomic regions. Genome Res. 2005, 15 (11): 1468-1476. 10.1101/gr.4398405.
Article
PubMed
CAS
PubMed Central
Google Scholar
Cheng F, Chen W, Richards E, Deng L, Zeng C: SNP@Evolution: a hierarchical database of positive selection on the human genome. BMC Evol Biol. 2009, 9: 221-10.1186/1471-2148-9-221.
Article
PubMed
PubMed Central
Google Scholar
Langergraber KE, Prüfer K, Rowney C, Boesch C, Crockford C, Fawcett K, Inoue E, Inoue-Muruyama M, Mitani JC, Muller MN, Robbins MM, Schubert G, Stoinski TS, Viola B, Watts D, Wittig RM, Wrangham RW, Zuberbühler K, Pääbo S, Vigilant L: Generation times in wild chimpanzees and gorillas suggest earlier divergence times in great ape and human evolution. Proc Natl Acad Sci U S A. 2012, 109 (39): 15716-15721. 10.1073/pnas.1211740109.
Article
PubMed
CAS
PubMed Central
Google Scholar