Investigating the reliability of molecular estimates of evolutionary time when substitution rates and speciation rates vary

Table 1 Simulation design

Simulation type	Speciation rates covary with substitution rates?	Brownian motion covariance	Punctuated burst of substitutions at nodes?
Unlinked	No	0	No
Continuous	Yes	0.0044	No
Punctuated	No	0	Yes

We lay out the conditions for each set of simulated trees. Each set consisted of 50 trees. Lineage-specific speciation rates and substitution rates evolve continuously through time via Brownian motion in all three studies. The three simulations differ in whether the covariance between speciation and substitution rates is greater than zero in the Brownian motion and whether an additional burst of substitutions occurs at nodes of the tree (speciation events)

ISSN: 2730-7182