Skip to main content

Table 1 Analysis of known typically highly conserved key residues and amino acid motifs

From: The crowns have eyes: multiple opsins found in the eyes of the crown-of-thorns starfish Acanthaster planci

A. planci Opsin Disulfide bonda (C110/C187) LxxxDb (79) Counterionc (E113/E181) Schiff based (K296) NPxxY(302)
C-opsin 1.1a (gbr.65.47.t1) C/C ICVAD Y/E K NPVIY
C-opsin 1.1b (gbr.508.2.t1) C/C VCVAD Y/− K NPVIY
C-opsin 1.2 (gbr.65.46.t1) C/F ISVGD Y/− R N----
C-opsin 1.3 (gbr.65.45.t1) L/C VCEA- Y/A K NPIIY
Go-opsin (gbr.470.6.t1) C/C MAVSD I/E K NPLIY
R-opsin (gbr.176.5.t1) C/C LAFSD Y/E K NPLVY
Chaopsin (gbr.176.10.t1) C/C LSGSD Y/E K NPIIY
Peropsin (gbr.31.87.t1) C/C ASAGD Y/E K NPLMF
RGR opsin (gbr.37.113.t1) C/C LCAGD Y/E K NAALQ
Neuropsin (gbr.37.57.t1) C/C LAVSD Y/E K NPIIY
  1. aMotif required for recognition of rhodopsin by G-protein [87]
  2. bMotif interacting with NPxxY motif upon receptor activation for structural constraints [88]
  3. cGlutamic acid residues stabilizing the Schiff base bond
  4. dLysine residue forming Shiff base bond with retinal Motif providing structural constraints in response to photoisomerization during formation of the G protein-activating Meta II [89]