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Table 3 P450 genotype and allele frequencies in a cold selection environment

From: The effect of three environmental conditions on the fitness of cytochrome P450 monooxygenase-mediated permethrin resistance in Culex pipiens quinquefasciatus

   Genotype frequency
Observed (Expected)
Allele frequency    
Cross Gen. SS RS RR S R na HWEb Driftb
A #1 F2 0.25 0.50 0.25 0.50 0.50    
  F4 0.46 (0.53) 0.54 (0.39) 0 (0.08) 0.73 0.27 280 <0.0001* <0.0001*
  F8 0.26 (0.38) 0.71 (0.47) 0.03 (0.15) 0.62 0.38 920 <0.0001* 0.0066
  F12 0.32 (0.44) 0.68 (0.45) 0 (0.11) 0.66 0.34 160 <0.0001* 0.1841
A #2 F2 0.25 0.50 0.25 0.50 0.50    
  F4 0.21 (0.21) 0.49 (0.49) 0.30 (0.30) 0.46 0.54 310 0.8320 0.1068
  F8 0.04 (0.17) 0.73 (0.48) 0.23 (0.35) 0.41 0.59 1280 <0.0001* 0.1716
  F12 0 (0.17) 0.84 (0.49) 0.16 (0.34) 0.42 0.58 1040 <0.0001* 0.3875
B #1 F2 0.25 0.50 0.25 0.50 0.50    
  F4 0.12 (0.22) 0.70 (0.50) 0.18 (0.28) 0.47 0.53 140 <0.0001* 0.2041
  F8 0.07 (0.28) 0.86 (0.50) 0.04 (0.22) 0.53 0.47 1160 <0.0001* 0.1204
  F12 0.27 (0.39) 0.71 (0.47) 0.02 (0.14) 0.63 0.37 560 <0.0001* 0.0284
B #2 F2 0.50 0.25 0.25 0.50 0.50    
  F4 0.45 (0.50) 0.52 (0.41) 0.03 (0.09) 0.71 0.29 270 <0.0001* <0.0001*
  F8 0.19 (0.27) 0.66 (0.50) 0.15 (0.23) 0.52 0.48 840 <0.0001* <0.0001*
  F12 0.23 (0.36) 0.74 (0.48) 0.03 (0.16) 0.60 0.40 800 <0.0001* 0.0529
  1. atotal number of 4th instar larvae used in genotype monitoring assay
  2. bNominal p-values are reported for the probability that the data fit the null hypothesis of Hardy-Weinberg equilibrium (or genetic drift)
  3. * indicates tests that remain statistically significant after Bonferonni correction over the entire experiment