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Table 4 Comparison of the resulting percentage of genes in each state for Sub-Only Model and Sub + Dos Model is shown below for 400 Generations and 4,000,000 Generations following whole-genome duplication

From: Dosage balance acts as a time-dependent selective barrier to subfunctionalization

Percentage of genes in each state

400 Generations

Sub-Only

4,000,000 Generations

Sub-Only

400 Generations

Sub + Dos

4,000,000 Generations

Sub + Dos

State 1: fully redundant (transient)

34.58%

0%

52.19%

0%

State 2: Loss of 1 enhancer (transient)

2.805%

0%

3.283%

0%

State 3: Loss of 2 enhancers on one copy (transient)

0.03559%

0%

0.03486%

0%

State 4: Loss of 3 enhancers on one copy (transient)

0.0001927%

0%

0.0001603%

0%

State S: Subfunctionalized (absorbing)

0.04339%

0.2557%

0.04053%

0.4687%

State Y: One copy pseudogenized (absorbing)

62.54%

99.74%

44.46%

99.53%