From: Dosage balance acts as a time-dependent selective barrier to subfunctionalization
Percentage of genes in each state | 400 Generations Sub-Only | 4,000,000 Generations Sub-Only | 400 Generations Sub + Dos | 4,000,000 Generations Sub + Dos |
---|---|---|---|---|
State 1: fully redundant (transient) | 34.58% | 0% | 52.19% | 0% |
State 2: Loss of 1 enhancer (transient) | 2.805% | 0% | 3.283% | 0% |
State 3: Loss of 2 enhancers on one copy (transient) | 0.03559% | 0% | 0.03486% | 0% |
State 4: Loss of 3 enhancers on one copy (transient) | 0.0001927% | 0% | 0.0001603% | 0% |
State S: Subfunctionalized (absorbing) | 0.04339% | 0.2557% | 0.04053% | 0.4687% |
State Y: One copy pseudogenized (absorbing) | 62.54% | 99.74% | 44.46% | 99.53% |