Table 1 Canonical Wnt signaling components in tardigrades. GenBank accession numbers and scaffold numbers are from previously published genome studies [71, 85]. An ortholog of Arrow was not found
Function | Ortholog | Protein accession numbers | Scaffold numbers | ||
|---|---|---|---|---|---|
H. exemplaris | R. varieornatus | H. exemplaris | R. varieornatus | ||
Ligand | Wnt2 | OWA52741.1 | – | scaffold0284 | – |
| Â | Wnt4 | OQV20568.1 | GAV00263.1 | scaffold0029 | BDGG01000006 |
| Â | Wnt5 | OQV25062.1 | GAU92975.1 | scaffold0004 | BDGG01000002 |
| Â | Wnt9 | OQV11710.1 | GAU97803.1 | scaffold0163 | BDGG01000004 |
| Â | Wnt11 | OQV21261.1 | GAU87525.1 | scaffold0024 | BDGG01000001 |
| Â | Wnt16A | OQV19782.1 | GAU94914.1 | scaffold0035 | BDGG01000003 |
| Â | Wnt16B | OQV22138.1 | GAV05665.1 | scaffold0019 | BDGG01000012 |
| Â | WntA | OQV17790.1 | GAU98124.1 | scaffold0056 | BDGG01000004 |
Transmembrane transport | Wntless | OQV19301.1 | GAV08953.1 | scaffold0041 | BDGG01000019 |
Receptor | Fz1 | OQV23182.1 | GAU93634.1 | scaffold0013 | BDGG01000002 |
| Â | Fz2 | OQV23168.1 | GAU93659.1 | scaffold0013 | BDGG01000002 |
| Â | Fz3 | OQV21307.1 | GAU87444.1 | scaffold0024 | BDGG01000001 |
| Â | Fz4 | OQV18791.1 | GAV00601.1 | scaffold0046 | BDGG01000006 |
|  | Arrow | – | – | – | – |
Signal transduction | Dishevelled | OQV23134.1 | GAV07421.1 | scaffold0013 | BDGG01000015 |
| Â | Armadillo | OWA50075.1 | GAV07811.1 | scaffold0181 | BDGG01000016 |
Transcription factor | Pangolin | OQV17172.1 | GAV07782.1 | scaffold0065 | BDGG01000016 |
cWnt inhibition | Shaggy | OQV18828.1 | GAU89015.1 | scaffold0045 | BDGG01000001 |
| Â | APC | OQV22882.1 | GAV03262.1 | scaffold0015 | BDGG01000009 |
| Â | Axin | OQV22259.1 | GAV03998.1 | scaffold0018 | BDGG01000010 |