Table 1 TLR genome/transcriptome survey results and classification of TLRs included in the phylogenetic analysis
From: The evolution of the metazoan Toll receptor family and its expression during protostome development
| Species | TLRs | V-type/scc | P-type/mcc | NC | References |
|---|---|---|---|---|---|
| Cnidaria | |||||
| Nematostella vectensis | 1 | 0 | 1 | 0 | L: [27] |
| Acropora digitifera | 4 | 1 | 3 | 0 | L: [72] |
| Acropora millepora | 1 | 0 | 1 | 0 | L: [72] |
| Orbicella faveolata | 1 | 0 | 1 | 0 | L: [83] |
| Xenacoelomorpha | |||||
| Xenoturbella profunda | 0 | 0 | 0 | 0 | G: Unpublished |
| Hofstenia miamia | 0 | 0 | 0 | 0 | G: GCA004352715 |
| Praesagittifera naikaiensis | 0 | 0 | 0 | 0 | G: PRJDB7329 |
| Isodiametra pulchra | 0 | 0 | 0 | 0 | G: Unpublished |
| Meara stichopi | 0 | 0 | 0 | 0 | G: Unpublished |
| Convolutriloba macropyga | 0 | 0 | 0 | 0 | T: [100] |
| Spiralia | |||||
| Bryozoa | |||||
| Membranipora membranacea | 6 | 4 | 1 | 1 | T: SRX1121923 |
| Bugula neritina | 0 | 0 | 0 | 0 | T: [101] |
| Cycliophora | |||||
| Symbion pandora | 0 | 0 | 0 | 0 | T: [102] |
| Annelida | |||||
| Galathowenia oculata | 39 | 18 | 12 | 9 | T: Unpublished |
| Eisenia fetida | 11 | 0 | 1 | 10 | T: SRX3108745 |
| Helobdella robusta | 4 | 1 | 3 | 0 | G: [103] |
| Phyllochaetopterus prolifica | 3 | 1 | 0 | 2 | L: [66] |
| Mollusca | |||||
| Crassostrea gigas | 12 | 10 | 2 | 0 | G: [104] |
| Octopus bimaculoides | 9 | 1 | 6 | 2 | G: [105] |
| Cyclina sinensis | 2 | 1 | 1 | 0 | L: [88] |
| Leptochiton rugatus | 1 | 0 | 0 | 1 | L: [66] |
| Biomphalaria glabrata | 27 | 16 | 10 | 1 | G: [87]/NCBI |
| Brachiopoda | |||||
| Terebratalia transversa | 15 | 4 | 4 | 7 | T: [100] |
| Hemithris psittacea | 6 | 3 | 1 | 2 | T: [66] |
| Lingula anatina | 25 | 15 | 7 | 3 | G: [106] |
| Micrognathozoa | |||||
| Limnogathia maerski | 0 | 0 | 0 | 0 | T: SRX1121929 |
| Gastrotricha | |||||
| Lepidodermella squamata | 0 | 0 | 0 | 0 | T: [107] |
| Macrodasys sp | 0 | 0 | 0 | 0 | T: [108] |
| Megadasys sp | 0 | 0 | 0 | 0 | T: [108] |
| Diuronotus aspetos | 0 | 0 | 0 | 0 | T: SRX1121926 |
| Mesodasys laticaudatus | 0 | 0 | 0 | 0 | T: SRX872416 |
| Nemertea | |||||
| Lineus longissimus | 10 | 7 | 2 | 1 | T: [100] |
| Lineus ruber | 6 | 2 | 3 | 1 | T: Unpublished |
| Notospermus geniculatus | 7 | 5 | 1 | 1 | G: [89] |
| Paranemertes peregrina | 2 | 1 | 0 | 1 | L: [66] |
| Phoronida | |||||
| Phoronopsis harmeri | 2 | 0 | 1 | 1 | T: SRX1121914 |
| Phoronis australis | 24 | 14 | 8 | 2 | G: [89] |
| Phoronis psammophila | 3 | 1 | 1 | 1 | L: [66] |
| Phoronis vancouverensis | 6 | 5 | 0 | 1 | L: [66] |
| Platyhelminthes | |||||
| Macrostomum lignano | 0 | 0 | 0 | 0 | G: [109] |
| Echinococcus multilocularis | 0 | 0 | 0 | 0 | G: [110] |
| Hymenolepis microstoma | 0 | 0 | 0 | 0 | G: [110] |
| Rotifera | |||||
| Epiphanes senta | 1 | 1 | 0 | 0 | T: Unpublished |
| Rotaria tardigrada | 0 | 0 | 0 | 0 | T: [111] |
| Echinorhynchus gadi | 0 | 0 | 0 | 0 | T: SRX1121912 |
| Macracanthorhynchus hirudinaceus | 0 | 0 | 0 | 0 | T: [108] |
| Ecdysozoa | |||||
| Priapulida | |||||
| Priapulus caudatus | 3 | 0 | 3 | 0 | T: [100] |
| Halicryptus spinulosus | 4 | 1 | 3 | 0 | T: [100] |
| Tardigrada | |||||
| Hypsibius exemplaris | 1 | 0 | 1 | 0 | G: [112] |
| Ramazzottius varieornatus | 1 | 0 | 1 | 0 | G: [113] |
| Onychophora | |||||
| Peripatopsis capensis | 1 | 0 | 0 | 1 | T: [114] |
| Nematoda | |||||
| Loa loa | 1 | 0 | 1 | 0 | G: [115] |
| Onchocerca volvulus | 1 | 0 | 1 | 0 | G: [116] |
| Caenorhabditis elegans | 1 | 0 | 1 | 0 | L: NCBI |
| Loricifera | |||||
| Armorloricus elegans | 2 | 1 | 1 | 0 | T: SRX1120677 |
| Arthropoda | |||||
| Daphnia pulex | 5 | 2 | 3 | 0 | G: [117] |
| Drosophila melanogaster | 9 | 1 | 8 | 0 | L: NCBI |
| Ixodes scapularis | 5 | 1 | 3 | 1 | L: [118] |
| Deuterostomia | |||||
| Tunicata | |||||
| Ciona intestinalis | 2 | 1 | 1 | 0 | L: [97] |
| Oikopleura dioica | 1 | 1 | 0 | 0 | L: [96] |
| Echinodermata | |||||
| Strongylocentrotus purpuratus | 8 | 7 | 1 | 0 | L: [64] |
| Craniata | |||||
| Homo sapiens | 10 | 10 | 0 | 0 | L: NCBI |