Fig. 6

Effect of GC content on “missing genes” in non-avian genomes. For each three genome comparisons (Panthera, a; Myotis, b; Crocodylia, c), the upper panel shows the GC content landscapes of the two species. In red, the species with the highest number of genes in the comparison is shown, while the less well annotated genome is shown in black. The lower panels represent the presence score, which was calculated for each gene as follows: − 1 = only present in the best annotated genome; 0 = present in both genomes; + 1 = only present in the least annotated genome. A sliding window of 101 genes was applied to the presence score and GC% showing a clearcut correlation between the two parameters. Thus, also in non-avian genomes a higher number of "missing" genes is found in regions with elevated GC%