Fig. 3

Conservation of the var gene var2csa in P. reichenowi, P. praefalciparum and P. falciparum. A Schematic showing the syntenic region of chromosome 12 in P. reichenowi, P. praefalciparum and three isolates of P. falciparum (SN01, 7G8 and 3D7). The positions of the single copy genes fikk12 and acs7 are shown and represent the border between the core genome and the highly variable subtelomeric domain. The orthologues of var2csa are aligned and boxed in blue. B Alignment of the amino acid sequence encoded by the uORF of var2csa from P. praefalciparum, P. reichenowi and three isolates of P. falciparum (SN01, 7G8 and 3D7)