Fig. 3

Schematic representation of the 10 collagen-like protein sequences identified in the proteome of the red coral biominerals. The collagen sequence identified in the Acropora millepora (UniProt accession number B8V7R6) organic matrix is included. a Schematic protein domain (described in the box below) representation of the different collagen proteins with their respective ID (CR_n). Colored circles indicate presence of the protein in different fractions as described in Fig. 2b. EGF-like epidermal growth factor-like, SP signal peptide, TSPN Thrombospondin N-terminal-like domain, vWA von Willebrand factor type A. Scale bars = 100 amino acids. b Genomic synteny of the CR_5, CR_39, and CR_38 genes and of the CR_9 and CR_35 genes; exons are in green boxes, introns are in blue lines, and intergenic sequences are in dotted lines. Scale bar = 1000 base pairs. c The overall proportion of collagen-like proteins and the most abundant protein, scleritin (CR_1), in each sample in percentage of weighted spectra