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Table 2 Differentially expressed candidate color genes in our transcriptome. Parentheses in the gene symbol column indicate the number of transcripts that mapped to a particular gene. The pathway column indicates what color or pattern production pathway this gene is a part of

From: Variation in pigmentation gene expression is associated with distinct aposematic color morphs in the poison frog Dendrobates auratus

Gene symbol q value Pathway Citation
adam17 (2) 0.0163; 0.0469 Melanocyte development [20]
arfgap1 (2) 0.00362; 0.0267 Putative guanine synthesis in iridophores [26]
arfgap3 (4) 0.00739; 0.0000123; 0.00132; 0.0282 Putative guanine synthesis in iridophores [26]
airc 0.0126 Guanine synthesis [27]
atic 0.0447 Guanine synthesis in iridophores [26]
atox1 0.00124 Melanogenesis [28]
atp12a 0.0296 Melanogenesis [29]
bbs2 0.0300 Melanosome transport [30]
bbs5 0.0447 Melanosome transport [30]
bmpr1b 0.0118 Inhibits melanogenesis [31]
brca1 0.0455 Alters pigmentation, produces piebald appearances in mice [32, 33]
ctr9 0.0280 Melanocyte assembly [34, 35]
dera   Guanine synthesis in iridophores [26]
dio2 (3) 0.0338; 0.0256; 0.000866 Thyroid hormone pathways, tenuous [36]
dtnbp1 (2) 0.00120; 0.0456 Melanosome biogenesis [37]
ednrb (2) 0.0035; 0.0005 Guanine synthesis in iridophores, melanoblast migration [26, 38]
egfr (2) 0.0197; 0.000566 Melanocyte pigmentation and differentiation [39]
fbxw4 (2) 0.00268; 0.0183 Melanophore organization [40, 41]
gart 0.0000494 Purine synthesis, affecting iridophores, xanthophores, and melanophores [42]
gas1 (2) 0.0264; 0.0191 Guanine synthesis in iridophores [26]
gne (2) 0.00571; 0.0361 Sialic acid pathway [43]
hps3 0.0202 Melanosome biogenesis [18]
itgb1 (2) 0.0191; 0.0469 Guanine synthesis in iridophores [26]
lef1 0.0190 Melanocyte differentiation and development, melanogenesis [44]
leo1 0.0000381 Melanocyte assembly [45]
mitf 0.0466 Melanocyte regulation [46]
mlph 0.00568 Melanosome transport [47]
mthfd1 0.0430 Purine synthesis [48]
mreg 0.0156 Melanosome transport [49]
notch1 (3) 0.00681; 0.0139; 0.0487 Melanocyte production [50, 51]
prtfdc1 0.00000672 Guanine synthesis [26]
qdpr 0.0372 Guanine and Pteridine synthesis [52, 53]
qnr-71 (2) 0.0316; 0.0262 Melanosomal protein [54, 55]
rab3d 0.0321 Putative guanine synthesis in iridophores [26]
rab7a 0.0319 Putative guanine synthesis in iridophores [26]
rabggta 0.000864 Guanine synthesis [56]
scarb2 0.0329 Putative guanine synthesis in iridophores [26]
shroom2 0.0142 Pigment accumulation [57, 58]
sox9 0.0228 Melanin production [59]
tbx15 0.00838 Pigmentation boundaries [60]
tyrp1 0.0200 Melanogenesis [61]
xdh (2) 0.0346; 0.0384 Pteridine synthesis [62]
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BMC Ecology and Evolution

ISSN: 2730-7182

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