Fig. 1
From: Origin and development of oligoadenylate synthetase immune system

Original OAS genes are not involved in the OAS/RNaseL antiviral pathway. Genes related to the OAS/RNaseL pathway are displayed. IFN, IFNR, STAT1, STAT2, and RNaseL (colored in gray) have not been found in lower Metazoa. OAS genes and JAK-like genes are widely distributed in lower Metazoa