Positive selection at sites of chemosensory genes is associated with the recent divergence and local ecological adaptation in cactophilic Drosophila

Table 2 Gene-wide tests of positive selection and McDonald-Kreitman test. A summary of P-values obtained for selection tests is shown for each gene. Results for McDonald-Kreitman test are shown for the whole gene as well as for each domain (Cytoplasmic, transmembrane or extracellular) (See Methods for abbreviations)

Gene	Codeml _M8	PARRIS	BUSTED	BSR	aBSREL	MK _Total	MK _Cyto	MK _Trans	MK _Extr
Gr63a	< 0.001	0.131	1.000	> 0.05	> 0.05	0.502	1.000	na	0.350
Or67c	< 0.001	0.000	0.629	> 0.05	> 0.05	0.015 ^b	0.084	1.000	na
Or83c1	< 0.001	0.280	0.996	> 0.05	> 0.05	0.885	1.000	0.662	1.000
Or83c2	< 0.001	0.017	0.053	0.014 ^a	0.040	0.001 ^c	0.011	0.661	0.109

Significant and marginally significant values after FDR correction are in bold
^a This test showed positive selection specific to D. mojavensis lineage
^b This test was also significant for pairwise comparisons using D. mojavensis populations (SON and BAJ) and D. arizonae but not with ancestral D. navojoa outgroup (Additional file 1: Table S5)
^c This test was also significant for pairwise comparisons using D. mojavensis populations (SON, BAJ and CAT) and D. arizonae as well as ancestral D. navojoa outgroup (Additional file 1: Table S5)
MK_Total: McDonald-Kreitman test for whole gene
MK_Cyto: McDonald-Kreitman test for cytoplasmic domain
MK_Trans: McDonald-Kreitman test for transmembrane domain
MK_Extr: McDonald-Kreitman test for extracellular domain

ISSN: 2730-7182