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Table 4 Genes/proteins from the TBEVHostDB that had four pairwise interactions with the other genes/proteins within the network

From: A database of human genes and a gene network involved in response to tick-borne encephalitis virus infection

The central gene/protein Dataset/Type of evidence Number of neighbors Neighbors Biological role of subnetwork
IFNAR1 Up- or down-regulated 4 TYK2, PEPD, IFNB1, IFNA2 Attenuation of interferon signaling pathway by viral protein NS5 targeting PEPD
CCR5 Allelic variant 4 CD4, CCL3, CCL4, CCL2 The entry of TBEV into the host cell/The proinflammatory and tissue damage pathway