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Table 4 Testing for correlated evolution between PTM sites from SG

From: Inferring Methionine Sulfoxidation and serine Phosphorylation crosstalk from Phylogenetic analyses

Protein

Sites

l(I)

l(D)

LRT

p-Value

N

eIF2α

S218-M222

−108.2

−100.2

15.9

0.003

233

Ataxin-2

S814-M815

−95.3

−89.8

10.9

0.027

215

Ataxin-2-like

S211-M215

−135.0

−120.8

28.3

10−5

215

Pumilio homolog 1

S124-M125

−38.9

−23.3

31.2

2.8 10−6

51

  1. The column ‘Sites’ gives the residue (S: serine and M: methionine) found at the indicated position in the human ortholog sequence. LRT stands for the likelihood ratio test statistics and N for the number of species included in the analyses. l(I): natural logarithm of the likelihood value for the model of independent evolution. l(D): natural logarithm of the likelihood value for the model of dependent evolution