Fig. 1
From: Evolutionary origin and function of NOX4-art, an arthropod specific NADPH oxidase
Maximum Likelihood phylogeny of aligned NOX proteins identified in our searches, species names and their accession numbers. Three well-supported clades have been highlighted in different colors: NOX5, NOX1-3 and NOX4/NOX4-art. The yellow square within NOX4 clade depicts the arthropod specific genes (NOX4-art). The Aedes aegypti and Anopheles gambiae genes have the same sequence as the ones used in Kawahara et al. 2007 [32] and are highlighted in a different color. Numbers on branches are bootstrap support values from 1000 replicates; only numbers above 50% are shown. Scale bar is substitutions per site. The image was created using iTOL [100]