Fig. 4
From: Human MFAP1 is a cryptic ortholog of the Saccharomyces cerevisiae Spp381 splicing factor
Domain organization and CD spectra of MFAP1 and Spp381. a Secondary structure prediction and domain organization of Spp381 from S. cerevisiae and of MFAP1 from H. sapiens, C. thermophilum and C. elegans. Red/gray bars – predicted α-helices/ß-strands; blue/yellow bars – predicted solvent exposed/buried regions; green bars – regions of predicted structural disorder. b, c CD spectra of hsMFAP1 and scSpp381. CD spectra (λ = 190–240 nm) at 4 °C (solid lines) and 90 °C (dashed lines) and CD melting curves (4–90 °C) at 222 nm of (b) hsMFAP130-344 and of (c) full-length scSpp381