Fig. 10
From: Evolutionary comparison of prenylation pathway in kinetoplastid Leishmania and its sister Leptomonas
a Ramachandran plot of the homology-modeled structure of Leishmania donovani Rabgeranylgeranyltransferase. The different colored areas indicate “disallowed” (white), “generously allowed” (light yellow), “additional allowed” (yellow), and “most favored” (red) regions. b The wiring diagram of β-subunit of LdGGTase-II was performed using the PDBsum server (http://www.ebi.ac.uk/thornton-srv/databases/pdbsum/). c Superimposed structures of L. donovani RabGGTase (cyan) with template 1LTX (magenta). d The binding mode of inhibitor NE10790 (Pink) in the docked complex of L. donovani RabGGTase (Cyan)