Fig. 4

Enrichment of genes with paralogs among developmentally regulated genes. a Percentage of genes in each of the five classes, defined by orthology relationship and expression pattern. For developmentally regulated genes (union of all genes found in biclusters), the strongest enrichment consists in a significant overrepresentation (P<10−27) in conserved multicopy genes (many-to-X). b Enrichment in genes with paralogs among individual biclusters. Nineteen out of 29 biclusters show a significant enrichment in genes with paralogs