Figure 6
From: Evolution of the class C GPCR Venus flytrap modules involved positive selected functional divergence
Reconstruction of the ancestral VFTMs from class C GPCRs. Nine extinct ancestral amino acid sequences were inferred from 38 aligned present-day sequences and NJ tree topologies. The three-dimensional (3D) structures of ancestors were modelled on the structure of rat VFTM mGluR1 [PDB: 1EWK].