Systematic analysis of insertions and deletions specific to nematode proteins and their proposed functional and evolutionary relevance

Table 2 Functional classification^a of protein families^b bearing indels conserved across members of nematodes

	Free-Living	Plant-parasitic	Animal-parasitic	P-value
	(227 families)	(82 families)	(53 families)	(Exact test)
Electron transport	1.30%	6.00%	0%	0.04
Signal transduction	9.30%	8.50%	3.80%	0.51
Carbohydrate metabolism	3.50%	8.50%	3.80%	0.21
Lipid, fatty acid, and steroid metabolism	6.60%	15.90%	5.60%	0.04
Proteolysis	7.00%	10.00%	3.80%	0.46
Protein modification	7.50%	8.50%	7.60%	0.96
Nucleoside, nucleotide, and nucleic acid metabolism	28.20%	28.00%	34.00%	0.58
Intercellular protein traffic	8.80%	6%	3.80%	0.48
Cell cycle	11%	8.50%	17.00%	0.31
Transport	4.40%	4.80%	3.80%	1.00

^a, Functional classification is based on the Panter protein classification system [92];
^b, Only proteins families with indels common to a nematode group are included.

ISSN: 2730-7182