Table 5 Human-chimpanzee amino acid substitutions in functional domains
Gene | Amino acid (Human-Chimpanzee) | Nucleotide (Human-Chimpanzee) | Functional Domain |
|---|---|---|---|
GRIN2A | S906N | AGC-AAC | N-glycosylation site |
GRIN3A | S30G | AGC-GGC | N-myristoylation site |
GRIN3A | D71G | GAC-GGC | N-myristoylation site (lost in humans) |
GRIN3A | I988V | ATA-GTA | Casein kinase II phosphorylation site. |
GRIN3B | A468V | GCG-GTG | N-glycosylation site |
GRIN3B | R727H | CGC-CAC | Protein kinase C phosphorylation site (acquired in humans) |
GRIK5 | I809V | ATC-GTC | Transmembrane |
GRM2 | A6G | GCG-GGG | N-myristoylation site |
GRM6 | Y612H | TAC-CAC | Transmembrane |
GRM6 | M714V | ATG-GTG | Transmembrane |
GRM8 | V653I | GTC-ATC | Transmembrane |