Figure 2From: Long-range regulation is a major driving force in maintaining genome integrityFeature selections. Diagram representing the different types of features used by our predictor. For the local density of functional elements, the categories are coding amniote, non-coding amniote, coding metatheria, non-coding methateria within a 2 Mb window. For each of these categories, the distance from the candidate breakpoint to the center of inter-marker region considered is taken in account and various weighting factors termed α are applied. The effect of an α factor of 2 is presented at the top of the figure. In that case markers close to the breakpoint have a high weight whereas distant markers only bring a small contribution. The functional association between regulatory regions and genes is a different category of features. Each non-coding element is associated with a set of genes depending on the value of the β factor, which determines how far the association between non-coding and coding regions will be considered (β = 2 is illustrated). For a given inter-marker region, the predictor will test if the region overlaps such associations. In total, 29 features are considered.Back to article page