| Negative auto-regulation | Positive auto-regulation | Dual auto-regulation | No auto-regulation |
---|
E. coli
| | | | |
Family size = 1 | 10 | 4 | 2 | 14 |
Family size >1 | 52 (25) | 20 (10) | 7 (7) | 46 (22) |
d
| 0.71 | 0.71 | 0.78 | 0.61 |
S. cerevisiae
| | | | |
Family size = 1 | 4 | 5 | 0 | 86 |
Family size >1 | 0 | 5 | 0 | 26 |
d
| 0 | 0.5 | 0 | 0.23 |
- The number of transcription factors belonging to gene families of Family size = 1 (unduplicated) or Family size>1 (duplicated) are given by species and type of auto-regulatory interaction. The number of independent gene families contributing members to the sample is given in parentheses. Duplicability (d) for each regulatory class was determined as d = 1-N(F = 1)/(N(F = 1)+N(F>1)) based on the number of independent families (see Lin et al. 2007). Note that estimates of d can become misleading for low sample sizes so that results should be interpreted with care. No internal comparison is significant at p < 0.05 using Fisher's exact tests.