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Table 2 Multi-locus HKA test results for AVPR1B exons.

From: A complex selection signature at the human AVPR1B gene

Region Fixed sub. MLHKA Multi-locus HKA
   YRI AA EU AS EU AS
   ka p b ka p b ka p b ka p b Lc p d Lc p d
Ex1 35 2.08 .086 2.06 .20 1.60 .54 0.66 .13 n.a.e n.a.e n.a.e n.a.e
Ex2 25 3.77 .0046 3.38 .0093 3.56 .011 3.50 .011 35 .001 44 <.001
  1. a k (selection parameter) values from MLHKA test; k<1 means a reduction in polymorphism while k>1 means an excess of nucleotide variation;
  2. b p values for the MLHKA test;
  3. c likelihood (sum of deviations) for multi-locus HKA test;
  4. d p values from demographic coalescent simulations for multi-locus HKA;
  5. e not analyzed.