Table 2 Substitutions rates and GC* calculated for fixed substitutions and SNPs
From: Both selective and neutral processes drive GC content evolution in the human genome
Substitution type | Fixed substitutions | SNPs | ||||
|---|---|---|---|---|---|---|
| Â | Low GC | High GC | p | Low GC | High GC | p |
A/T -> C/G | 0.00049 | 0.00057 | 4.1 × 10-1 | 0.00020 | 0.00014 | 7.6 × 10-1 |
A/T -> G/C | 0.00214 | 0.00257 | 6.9 × 10-2 | 0.00069 | 0.00074 | 7.3 × 10-1 |
A/T -> T/A | 0.00049 | 0.00043 | 5.0 × 10-1 | 0.00018 | 0.00014 | 6.6 × 10-1 |
C/G -> G/C | 0.00088 | 0.00080 | 5.5 × 10-1 | 0.00031 | 0.00028 | 9.0 × 10-1 |
C/G -> A/T | 0.00095 | 0.00075 | 1.3 × 10-1 | 0.00035 | 0.00027 | 2.9 × 10-1 |
C/G -> T/A | 0.00275 | 0.00268 | 7.3 × 10-1 | 0.00105 | 0.00109 | 1 |
CpG -> TpG | 0.03226 | 0.02081 | 7.3 × 10-3 | 0.01464 | 0.01300 | 6.7 × 10-1 |
GC* | 0.35548 | 0.41816 | 1.3 × 10-4 | 0.35703 | 0.38604 | 3.7 × 10-1 |
Number of sites (Mb) | 0.96 | 0.44 | - | 0.96 | 0.44 | - |