Table 1 Vertebrate bestrophin homologues (n = 53) used for phylogenetic analysis
From: Molecular evolution and functional divergence of the bestrophin protein family
No. | Protein Name | Short name | Organism | Taxonomy | Amino acids | Gene bank identifier | cDNA Acc. No. |
|---|---|---|---|---|---|---|---|
1 | Bestrophin 1 | HsB1 | Homo sapiens | Mammalia | 585 | NP_004174 | AF073501 |
2 | Bestrophin 2 | HsB2 | Â | Â | 509 | AAR99655 | AY515705 |
3 | Bestrophin 3 | HsB3 | Â | Â | 668 | NP_116124 | NM_032735 |
4 | Bestrophin 4 | HsB4 | Â | Â | 473 | NP_695006 | NM_153274 |
5 | Bestrophin 1 | PtB1 | Pan troglodytes | Mammalia | 585 | XP_001151529 | XM_001151529 |
6 | Bestrophin 2 | PtB2 | Â | Â | 509 | XP_512414 | XM_512414 |
7 | Bestrophin 3 | PtB3 | Â | Â | 668 | XP_522466 | XM_522466 |
8 | Bestrophin 4 | PtB4 | Â | Â | 473 | XP_524571 | XM_524571 |
9 | Bestrophin 1 | MmB1 | Macaca mulatta | Mammalia | 585 | XP_001116583 | XM_001116583 |
10 | Bestrophin 2 | MmB2 | Â | Â | 509 | XP_001108800 | XM_001108800 |
11 | Bestrophin 3 | MmB3 | Â | Â | 669 | XP_001117392 | XM_001117392 |
12 | Bestrophin 4 | MmB4 | Â | Â | 473 | XP_001098771 | XM_001098771 |
13 | Bestrophin 1 | MfB1 | Macaca fascicularis | Mammalia | 585 | AAQ56049 | AY357925 |
14 | Bestrophin 1 | BtB1 | Bos taurus | Mammalia | 589 | XP_585778 | XM_585778 |
15 | Bestrophin 2 | BtB2 | Â | Â | 528 | XP_607911 | XM_607911 |
16 | Bestrophin 3 | BtB3 | Â | Â | 369 | XP_613863 | XM_613863 |
17 | Bestrophin 4 | BtB4 | Â | Â | 467 | XP_587691 | XM_587691 |
18 | Bestrophin 3 | LaB3 | Loxodonta africana | Mammalia | 674 | ENSLAFP00000000778 | ENSLAFT00000000928 |
19 | Bestrophin 2 | FcB2 | Felis catus | Mammalia | 488 | ENSFCAP00000000436 | ENSFCAT00000000470 |
20 | Bestrophin 1 | CfB1 | Canis familiaris | Mammalia | 693 | XP_540912 | XM_540912 |
21 | Bestrophin 2 | CfB2 | Â | Â | 509 | XP_542045 | XM_542045 |
22 | Bestrophin 4 | CfB4 | Â | Â | 437 | XP_539638 | XM_539638 |
23 | Bestrophin 1 | MsB1 | Mus musculus | Mammalia | 551 | NP_036043 | NM_011913 |
24 | Bestrophin 2 | MsB2 | Â | Â | 508 | AAS09923 | AY450428 |
25 | Bestrophin 3 | MsB3 | Â | Â | 669 | NP_001007584 | NM_001007583 |
26 | Bestrophin 1 | RnB1 | Rattus norvegicus | Mammalia | 550 | NP_001011940 | NM_001011940 |
27 | Bestrophin 2 | RnB2 | Â | Â | 508 | XP_001070841 | XM_001070841 |
28 | Bestrophin 3 | RnB3 | Â | Â | 672 | XP_235161 | XM_235161 |
29 | Bestrophin 4 | RnB4 | Â | Â | 454 | XP_001066317 | XM_001066317 |
30 | Bestrophin 1 | MdB1 | Monodelphis domestica | Mammalia | 467 | XP_001363751 | XM_001363714 |
31 | Bestrophin 3 | MdB3 | Â | Â | 676 | XP_001369557 | XM_001369520 |
32 | Bestrophin 4 | MdB4 | Â | Â | 487 | XP_001376079 | XM_001376042 |
33 | Bestrophin 4 | OgB4 | Otolemur garnettii | Mammalia | 471 | ENSOGAP00000006199 | ENSOGAT00000006927 |
34 | Bestrophin 4 | MlB4 | Myotis lucifugus | Mammalia | 473 | ENSMLUP00000001435 | ENSMLUT00000001564 |
35 | Bestrophin 3 | OaB3 | Ornithorhynchus anatinus | Â | 675 | ENSOANP00000009484 | ENSOANT00000009486 |
36 | Bestrophin 1 | GgB1 | Gallus gallus | Aves | 762 | XP_421055 | XM_421055 |
37 | Bestrophin 3 | GgB3 | Â | Â | 669 | XP_416091 | XM_416091 |
38 | Bestrophin 4 | GgB4 | Â | Â | 488 | XP_001234941 | XM_001234940 |
39 | Bestrophin 1 | Xt-1 | Xenopus tropicalis | Amphibia | 419 | ENSXETP00000014724 | ENSXETT00000014724 |
40 | Bestrophin 2 | Xt-2 | Â | Â | 510 | NP_988974 | NM_203643 |
41 | Bestrophin 3 | Xt-3 | Â | Â | 366 | ENSXETP00000002984 | ENSXETT00000002984 |
42 | Bestrophin 4 | Xt-4 | Â | Â | 367 | ENSXETP00000029791 | ENSXETT00000029791 |
43 | Bestrophin 1 | Tr-1 | Takifugu rubripes | Actinopterygii | 369 | SINFRUP00000141703 | SINFRUT00000141703 |
44 | Bestrophin 2 | Tr-2 | Â | Â | 431 | SINFRUP00000151123 | SINFRUT00000151123 |
45 | Bestrophin 3 | Tr-3 | Â | Â | 407 | SINFRUP00000181928 | SINFRUT00000182495 |
46 | Bestrophin 4 | Tr-4 | Â | Â | 370 | SINFRUP00000134584 | SINFRUT00000134584 |
47 | Bestrophin 1 | DrB1 | Danio rerio | Actinopterygii | 367 | XP_689098 | XM_684006 |
48 | Bestrophin 2 | DrB2 | Â | Â | 589 | XP_695597 | XM_690505 |
49 | Bestrophin 1 | Tn-1 | Tetraodon igrovoridis | Actinopterygii | 572 | CAG08784 | CAAE01015000 |
50 | Bestrophin 2 | Tn-2 | Â | Â | 431 | CAG03298 | CAAE01014712 |
51 | Bestrophin 2 | Ga-2 | Gasterosteus culeatus | Actinopterygii | 368 | ENSGACP00000025248 | ENSGACT00000025297 |
52 | Bestrophin 3 | Ga-3 | Â | Â | 367 | ENSGACP00000019354 | ENSGACT00000019392 |
53 | Bestrophin 1 | Ol-1 | Oryzias latipes | Actinopterygii | 454 | ENSORLP00000007714 | ENSORLT00000007715 |