Skip to main content

Table 1 Vertebrate bestrophin homologues (n = 53) used for phylogenetic analysis

From: Molecular evolution and functional divergence of the bestrophin protein family

No. Protein Name Short name Organism Taxonomy Amino acids Gene bank identifier cDNA Acc. No.
1 Bestrophin 1 HsB1 Homo sapiens Mammalia 585 NP_004174 AF073501
2 Bestrophin 2 HsB2    509 AAR99655 AY515705
3 Bestrophin 3 HsB3    668 NP_116124 NM_032735
4 Bestrophin 4 HsB4    473 NP_695006 NM_153274
5 Bestrophin 1 PtB1 Pan troglodytes Mammalia 585 XP_001151529 XM_001151529
6 Bestrophin 2 PtB2    509 XP_512414 XM_512414
7 Bestrophin 3 PtB3    668 XP_522466 XM_522466
8 Bestrophin 4 PtB4    473 XP_524571 XM_524571
9 Bestrophin 1 MmB1 Macaca mulatta Mammalia 585 XP_001116583 XM_001116583
10 Bestrophin 2 MmB2    509 XP_001108800 XM_001108800
11 Bestrophin 3 MmB3    669 XP_001117392 XM_001117392
12 Bestrophin 4 MmB4    473 XP_001098771 XM_001098771
13 Bestrophin 1 MfB1 Macaca fascicularis Mammalia 585 AAQ56049 AY357925
14 Bestrophin 1 BtB1 Bos taurus Mammalia 589 XP_585778 XM_585778
15 Bestrophin 2 BtB2    528 XP_607911 XM_607911
16 Bestrophin 3 BtB3    369 XP_613863 XM_613863
17 Bestrophin 4 BtB4    467 XP_587691 XM_587691
18 Bestrophin 3 LaB3 Loxodonta africana Mammalia 674 ENSLAFP00000000778 ENSLAFT00000000928
19 Bestrophin 2 FcB2 Felis catus Mammalia 488 ENSFCAP00000000436 ENSFCAT00000000470
20 Bestrophin 1 CfB1 Canis familiaris Mammalia 693 XP_540912 XM_540912
21 Bestrophin 2 CfB2    509 XP_542045 XM_542045
22 Bestrophin 4 CfB4    437 XP_539638 XM_539638
23 Bestrophin 1 MsB1 Mus musculus Mammalia 551 NP_036043 NM_011913
24 Bestrophin 2 MsB2    508 AAS09923 AY450428
25 Bestrophin 3 MsB3    669 NP_001007584 NM_001007583
26 Bestrophin 1 RnB1 Rattus norvegicus Mammalia 550 NP_001011940 NM_001011940
27 Bestrophin 2 RnB2    508 XP_001070841 XM_001070841
28 Bestrophin 3 RnB3    672 XP_235161 XM_235161
29 Bestrophin 4 RnB4    454 XP_001066317 XM_001066317
30 Bestrophin 1 MdB1 Monodelphis domestica Mammalia 467 XP_001363751 XM_001363714
31 Bestrophin 3 MdB3    676 XP_001369557 XM_001369520
32 Bestrophin 4 MdB4    487 XP_001376079 XM_001376042
33 Bestrophin 4 OgB4 Otolemur garnettii Mammalia 471 ENSOGAP00000006199 ENSOGAT00000006927
34 Bestrophin 4 MlB4 Myotis lucifugus Mammalia 473 ENSMLUP00000001435 ENSMLUT00000001564
35 Bestrophin 3 OaB3 Ornithorhynchus anatinus   675 ENSOANP00000009484 ENSOANT00000009486
36 Bestrophin 1 GgB1 Gallus gallus Aves 762 XP_421055 XM_421055
37 Bestrophin 3 GgB3    669 XP_416091 XM_416091
38 Bestrophin 4 GgB4    488 XP_001234941 XM_001234940
39 Bestrophin 1 Xt-1 Xenopus tropicalis Amphibia 419 ENSXETP00000014724 ENSXETT00000014724
40 Bestrophin 2 Xt-2    510 NP_988974 NM_203643
41 Bestrophin 3 Xt-3    366 ENSXETP00000002984 ENSXETT00000002984
42 Bestrophin 4 Xt-4    367 ENSXETP00000029791 ENSXETT00000029791
43 Bestrophin 1 Tr-1 Takifugu rubripes Actinopterygii 369 SINFRUP00000141703 SINFRUT00000141703
44 Bestrophin 2 Tr-2    431 SINFRUP00000151123 SINFRUT00000151123
45 Bestrophin 3 Tr-3    407 SINFRUP00000181928 SINFRUT00000182495
46 Bestrophin 4 Tr-4    370 SINFRUP00000134584 SINFRUT00000134584
47 Bestrophin 1 DrB1 Danio rerio Actinopterygii 367 XP_689098 XM_684006
48 Bestrophin 2 DrB2    589 XP_695597 XM_690505
49 Bestrophin 1 Tn-1 Tetraodon igrovoridis Actinopterygii 572 CAG08784 CAAE01015000
50 Bestrophin 2 Tn-2    431 CAG03298 CAAE01014712
51 Bestrophin 2 Ga-2 Gasterosteus culeatus Actinopterygii 368 ENSGACP00000025248 ENSGACT00000025297
52 Bestrophin 3 Ga-3    367 ENSGACP00000019354 ENSGACT00000019392
53 Bestrophin 1 Ol-1 Oryzias latipes Actinopterygii 454 ENSORLP00000007714 ENSORLT00000007715