Figure 3From: Molecular evolution and functional divergence of the bestrophin protein familySite specific profiles for evolutionary rate changes in the vertebrate bestrophin protein family. A, The posterior probabilities of functional divergence for vertebrate bestrophins 1 to 4 were obtained with Diverge [27]. Individual cut-off values for each comparison are marked with red horizontal lines. B, Residues with predicted functional divergence between bestrophin subfamilies are mapped onto the membrane topology models of bestrophin 4 (top) and bestrophin 2 (bottom). Divergent amino acids are shown and listed in Table 4. In the model drawing, residues excluded from the analysis are depicted in gray.Back to article page