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Figure 5 | BMC Evolutionary Biology

Figure 5

From: Evolutionary history of the alpha2,8-sialyltransferase (ST8Sia) gene family: Tandem duplications in early deuterostomes explain most of the diversity found in the vertebrate ST8Sia genes

Figure 5

Polysialyltransferase domain (PSTD) found in vertebrate ST8Sia II and ST8Sia IV and in invertebrate sequences and the two new motifs specific to the ST8Sia III subfamilies. The catalytic domain of the sialyltransferases is indicated by the grey rectangles, the sialylmotifs L, S, III and VS by blue boxes and the a and b motifs by yellow boxes. The conserved peptide sequences used to generate the sequence logos of motif II/IV, motif III-1 and motif III-2 were extracted from multiple sequence alignments of vertebrate and invertebrate sequences. The overall height of the stack indicates the sequence conservation at a given position, while the height of symbols within the stack indicates the relative frequency of each amino acid at that position [69, 70]. In the logos, amino acids are colored according to their chemical properties. The PSTD, which is included in the larger motif II/IV is shown with the orange background.

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BMC Ecology and Evolution

ISSN: 2730-7182

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