Lineage of origin | Super pathway | Pathway (pathway identifier) | T | U | E | M | V |
---|---|---|---|---|---|---|---|
Pre- eukaryotic origin (universal pathways) | Carbohydrate metabolism | Glyoxylate & dicarboxylate metabolism (00630) | 11(3) | 9(3) | 1(0) | 0(0) | 1(0) |
 |  | Galactose metabolism (00052) | 15(3) | 11(1) | 1(0) | 0(0) | 3(2) |
 |  | Fructose & mannose metabolism (00051) | 17(11) | 11(6) | 4(3) | 1(1) | 1(1) |
 |  | Pentose phosphate pathway (00030) | 16(6) | 16(6) | 0(0) | 0(0) | 0(0) |
 |  | Aminosugars metabolism (00530) | 17(12) | 11(9) | 4(2) | 1(0) | 1(1) |
 |  | Pyruvate metabolism (00620) | 21(5) | 20(5) | 1(0) | 0(0) | 0(0) |
 |  | Butanoate metabolism (00650) | 17(3) | 14(1) | 1(1) | 1(0) | 1(1) |
 |  | Glycolysis/Gluconeogenesis (00010) | 27(5) | 22(3) | 2(0) | 2(2) | 1(0) |
 |  | Starch &sucrose metabolism (00500) | 23(8) | 15(6) | 3(1) | 1(0) | 4(1) |
 |  | Citrate cycle (TCA cycle) (00020) | 16(1) | 14(1) | 2(0) | 0(0) | 0(0) |
 | Energy metabolism | Sulfur metabolism (00920) | 8(3) | 3(1) | 1(1) | 0(0) | 4(1) |
 |  | Oxidative phosphorylation (00190) | 8(4) | 7(3) | 1(1) | 0(0) | 0(0) |
 |  | Nitrogen metabolism (00910) | 9(1) | 8(1) | 1(0) | 0(0) | 0(0) |
 |  | Methane metabolism (00680) | 5(1) | 5(1) | 0(0) | 0(0) | 0(0) |
 | Lipid metabolism | Biosynthesis of steroids (00100) | 17(11) | 9(5) | 6(4) | 0(0) | 2(2) |
 |  | Fatty acid metabolism (00071) | 17(1) | 14(1) | 2(0) | 0(0) | 1(0) |
 |  | Linoleic acid metabolism (00591) | 5(1) | 2(1) | 1(0) | 0(0) | 2(0) |
 |  | Glycerolipid metabolism (00561) | 16(4) | 12(2) | 3(2) | 0(0) | 1(0) |
 |  | Glycerophospholipid metabolism (00564) | 23(9) | 9(3) | 11(3) | 1(1) | 2(2) |
 |  | Ether lipid metabolism (00565) | 7(2) | 2(1) | 5(1) | 0(0) | 0(0) |
 |  | Fatty acid biosynthesis (00061) | 11(9) | 7(6) | 4(3) | 0(0) | 0(0) |
 | Nucleotide metabolism | Purine metabolism (00230) | 51(24) | 41(20) | 8(4) | 0(0) | 2(0) |
 |  | Pyrimidine metabolism (00240) | 34(14) | 29(13) | 3(0) | 0(0) | 2(1) |
 | Amino acid metabolism | Methionine metabolism (00271) | 13(2) | 11(2) | 1(0) | 0(0) | 1(0) |
 |  | Histidine metabolism (00340) | 14(4) | 11(3) | 1(0) | 0(0) | 2(1) |
 |  | Arginine &proline metabolism (00330) | 19(5) | 15(4) | 2(0) | 1(1) | 1(0) |
 |  | Lysine degradation (00300) | 19(7) | 10(1) | 4(2) | 1(1) | 4(3) |
 |  | Urea cycle & metabolism of amino groups (00220) | 21(7) | 17(7) | 3(0) | 0(0) | 1(0) |
 |  | Valine, leucine & isoleucine degradation (00280) | 23(7) | 19(5) | 0(0) | 0(0) | 4(2) |
 |  | Tryptophan metabolism (00380) | 25(11) | 16(4) | 4(4) | 0(0) | 5(3) |
 |  | Cysteine metabolism (00272) | 7(1) | 6(1) | 1(0) | 0(0) | 0(0) |
 |  | Phenylalanine, tyrosine &tryptophan biosynthesis (00360) | 6(1) | 5(1) | 1(0) | 0(0) | 0(0) |
 |  | Glycine, serine &threonine metabolism (00260) | 31(10) | 24(7) | 2(0) | 2(2) | 3(1) |
 | Metabolism of other amino acids | Glutathione metabolism (00480) | 10(1) | 10(1) | 0(0) | 0(0) | 0(0) |
 |  | Selenoamino acid metabolism (00450) | 10(2) | 10(2) | 0(0) | 0(0) | 0(0) |
 | Glycan biosynthesis & metabolism | N-Glycan biosynthesis (00510) | 21(3) | 2(1) | 13(2) | 4(0) | 2(0) |
 | Metabolism of cofactors & vitamins | Vitamin B6 metabolism (00750) | 5(3) | 3(2) | 0(0) | 0(0) | 2(1) |
 |  | Folate biosynthesis (00790) | 8(6) | 6(4) | 2(2) | 0(0) | 0(0) |
 |  | Riboflavin metabolism (00740) | 5(2) | 3(2) | 0(0) | 1(0) | 1(0) |
 |  | Biotin metabolism(00780) | 5(5) | 1(1) | 3(3) | 1(1) | 0(0) |
 |  | Porphyrin & chlorophyll metabolism (00860) | 16(12) | 13(10) | 1(1) | 1(0) | 1(1) |
 |  | Nicotinate & nicotinamide metabolism (00760) | 13(7) | 7(4) | 0(0) | 0(0) | 6(3) |
 |  | One carbon pool by folate (00670) | 17(4) | 15(2) | 1(1) | 1(1) | 0(0) |
 |  | Pantothenate & CoA biosynthesis (00770) | 12(6) | 10(5) | 0(0) | 0(0) | 2(1) |
Eukaryotic origin | Carbohydrate metabolism | Inositol phosphate metabolism (00031) | 16(3) | 2(0) | 11(2) | 1(1) | 2(0) |
 | Lipid metabolism | C21-Steroid hormone metabolism (00140) | 10(4) | 0(0) | 2(1) | 0(0) | 8(3) |
 |  | Androgen &estrogen metabolism (00150) | 13(2) | 1(0) | 3(1) | 1(0) | 8(1) |
 |  | Arachidonic acid metabolism (00590) | 20(12) | 4(0) | 6(5) | 0(0) | 10(7) |
 |  | Fatty acid elongation in mitochondria (00062) | 6(2) | 3(0) | 2(2) | 0(0) | 1(0) |
 |  | Sphingolipid metabolism (00600) | 19(11) | 6(0) | 7(5) | 1(1) | 5(5) |
 |  | Bile acid biosynthesis (00120) | 12(2) | 3(0) | 3(2) | 0(0) | 6(0) |
 | Amino acid metabolism | Alanine &aspartate metabolism (00252) | 21(2) | 18(0) | 3(2) | 0(0) | 0(0) |
 |  | Tyrosine metabolism (00350) | 20(4) | 9(0) | 3(1) | 2(1) | 6(2) |
 | Glycan biosynthesis & metabolism | Glycan structures – biosynthesis 1 (01030) | 43(1) | 1(0) | 12(1) | 14(0) | 16(0) |
 |  | Glycosylphosphatidylinositol(GPI)- anchor biosynthesis (00563) | 3(1) | 0(0) | 3(1) | 0(0) | 0(0) |
 | Metabolism of cofactors & vitamins | Retinol metabolism (00830) | 3(3) | 0(0) | 1(1) | 1(1) | 1(1) |
 | Xenobiotics Biodegradation & metabolism | Metabolism of xenobiotics by cytochrome P450 (00980) | 7(2) | 3(0) | 3(2) | 1(0) | 0(0) |
Metazoan- origin | Metabolism of other amino acids | Taurine &hypotaurine metabolism (00430) | 5(1) | 2(0) | 1(0) | 1(1) | 1(0) |
 | Glycan biosynthesis & metabolism | Heparan sulfate biosynthesis (00534) | 7(1) | 0(0) | 0(0) | 5(1) | 2(0) |
Vertebrate- origin | Carbohydrate metabolism | Nucleotide sugars metabolism (00520) | 6(0) | 5(0) | 0(0) | 0(0) | 1(0) |
 |  | Pentose & glucuronate interconversions (00040) | 7(1) | 5(0) | 0(0) | 1(0) | 1(1) |
 |  | Propanoate metabolism (00640) | 15(0) | 13(0) | 1(0) | 0(0) | 1(0) |
 | Amino acid metabolism | Lysine biosynthesis (00300) | 5(0) | 2(0) | 2(0) | 0(0) | 1(0) |
 |  | Phenylalanine metabolism (00360) | 9(0) | 6(0) | 2(0) | 0(0) | 1(0) |
 | Metabolism of other amino acids | beta-Alanine metabolism (00410) | 14(0) | 11(0) | 2(0) | 0(0) | 1(0) |
 | Glycan biosynthesis & metabolism | Glycan structures – degradation (01032) | 18(0) | 10(0) | 2(0) | 0(0) | 6(0) |
 |  | Glycosphingolipid biosynthesis – globoseries (00603) | 10(1) | 2(0) | 1(0) | 1(0) | 6(1) |
 |  | Glycosaminoglycan degradation (00531) | 11(0) | 4(0) | 1(0) | 0(0) | 6(0) |
 |  | Glycosphingolipid biosynthesis – lactoseries (00601) | 7(0) | 0(0) | 1(0) | 0(0) | 6(0) |
 |  | Keratan sulfate biosynthesis (00533) | 5(0) | 0(0) | 0(0) | 2(0) | 3(0) |
 |  | Glycosphingolipid biosynthesis – neo-lactoseries (00602) | 10(0) | 0(0) | 1(0) | 2(0) | 7(0) |
 |  | Glycan structure – biosynthesis 2 (01031) | 22(0) | 1(0) | 3(0) | 2(0) | 16(0) |
 |  | O-Glycan biosynthesis (00512) | 6(0) | 0(0) | 0(0) | 1(0) | 5(0) |
 |  | Glycosphingolipid biosynthesis – ganglioseries (00604) | 8(0) | 2(0) | 0(0) | 0(0) | 6(0) |
 |  | Chondroitin sulfate biosynthesis (00532) | 10(0) | 0(0) | 0(0) | 4(0) | 6(0) |
 | Biosynthesis of secondary metabolites | Limonene & pinene degradation (00903) | 5(0) | 2(0) | 0(0) | 0(0) | 3(0) |
 |  | Monoterpenoid biosynthesis (00902) | 3(0) | 0(0) | 0(0) | 0(0) | 3(0) |
 | Xenobiotics biodegradation & metabolism | gamma-Hexachlorocyclohexane degradation (00361) | 5(1) | 4(0) | 0(0) | 0(0) | 1(1) |