Core motifs C1 through C7 of C domain subtypes LC
, Starter, DC
and Dual E/C domains. Compared to Marahiel et al. , motifs are extended in both directions to include more significantly conserved positions. Yellow bars indicate significant specificity determining positions between LCL, Starter and DCL domains; those with red stars on top are the most significant positions. Numbers above the letter stacks indicate residues of functional and structural importance refered to in Subsection "Key residues in Condensation domains" and Table 1.