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Figure 4 | BMC Evolutionary Biology

Figure 4

From: Tracing the origin of functional and conserved domains in the human proteome: implications for protein evolution at the modular level

Figure 4

Cartoon diagram of different representative proteins containing Pfam-A family EGF (epidermal growth factor) with remote homologs found at different nodes along the lineage using subtractive searching method. For each sequence, SWISS-PROT identifier is given and EGF domain is shown along with the node name where it has found its remote homolog in that protein sequence. The codes for different nodes are: B, bacteria; E, eukaryota; T, metazoa; C, chordata; M, mammalia; P, primates; H, Homo sapiens. Other functionally significant domain names in protein sequences are given in the legend.

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BMC Ecology and Evolution

ISSN: 2730-7182

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