Figure 7
From: Phylogenetic analysis of the tenascin gene family: evidence of origin early in the chordate lineage
Xenopus tropicalis tenascins. Four tenascins were identified in the X. tropicalis genome. Stick diagrams of the three complete sequences are shown here. The X. tropicalis tenascin-C gene encodes 14.5 EGF-like repeats and 8 FN type III domains. There are no RGD motifs. The domain represented by an oval between the second and third FN type III domains shares sequences similarities with the DUF612 domain of pufferfish tenascin-X and the SP-domain of avian and mammalian tenascin-X. The amphibian tenascin-W contains an RGD domain in an exposed loop in the fourth FN type III domain and a KGD motif in the fifth FN type III domain; these domains appear to have undergone a recent duplication.