Figure 4
From: Phylogenetic analysis of the tenascin gene family: evidence of origin early in the chordate lineage
Tetraodon nigroviridis tenascin-X. A. The predicted amino acid sequence of T. nigroviridis tenascin-X. Putative heptad repeats (underlined) are found near the N-terminus. Between amino acids 41 and 86 are one complete are two partial EGF-like repeats. This is followed by a short (48 amino acid) linking region and 7 complete and two partial GK repeats (between amino acids 135 and 270). Between the GK repeats and amino acid 571 is a region rich in charged amino acids. Three complete and one partial FN type III domains are found between amino acids 572 and 884. There is a FReD at the C-terminus. B. The repeat and domain organization of pufferfish tenascin-X. The region between amino acids 87 and 571 is similar to the DUF612 domain of UNC-89. C. The T. nigroviridis tenascin-X gene (TNX) is found between the genes encoding cytochrome p450 21-hydroxylase (cp450), C4 complement and retinoid X receptor beta (RXRB). The same genes overlap or flank tenascin-X genes in birds and mammals.