Figure 2

The E(spl)-C in mosquito A. gambiae. (A) The E(spl)-C in the mosquito is composed of two putative genes, A.g.mβ and A.g.mα. Approximately 100 kb away a second bHLH coding gene was detected, however, the analysis predicted a close relationship to Deadpan and Hairy. Since a good fitting hairy ortholog is elsewhere in the mosquito genome, the gene is most likely a dpn ortholog. B) Alignment between A.g.Mβ and D.m.Mβ shows good conservation within the bHLH and the orange domains (marked) as well as the WRPW motif at the C-terminus. Identical residues are marked in blue; red shows highly related and yellow similar residues.