Table 7 Animal and yeast clusters

57

3.3E-7

Myosin heavy chain XVIII

non-muscle and smooth muscle myosins

C.e., D.m., H.s., M.m., S.p.

50

6.5E-8

Myosin heavy chain type 2

actin motor protein (cytoskeleton)

C.e., D.m., H.s., M.m., S.c., S.p.

27

<E-40

Dynein heavy chain

MT motor (cytoskeleton, flagella)

C.e., D.m., H.s., M.m., S.c.

17

3.1E-9

Intersectins, Eps15

endocytosis

C.e., D.m., H.s., M.m., S.c., S.p.

16

9.5E-7

Png-1, IF-2, Neurofilament triplet L, Troponin T

D.m., H.s., M.m., O.s., S.c.

14

<E-40

Restin, Dynactin, CLIP proteins

linking endocytic vesicles to MTs (IF cytoskeleton), dynein activator (MTs in neurons), MT/IF associated (cytoskeleton)

C.e., D.m., H.s., M.m., S.c., S.p.

14

1.6E-15

Myosin heavy chain V

unusual myosin

C.e., D.m., H.s., M.m., S.c.

14

<E-40

DRFs

binds Rho-GTP and profilin, promotes actin polymerization (membrane cytoskeleton)

D.m., H.s., M.m., S.c.