Figure 1
From: The complexity of selection at the major primate β-defensin locus
Phylogenetic tree relating primate and mouse β-defensin proteins constructed using neighbour-joining. Branches with less than 50% bootstrap support have been collapsed. Species and families of interest are coloured as follows: mouse sequences are red, human sequences are dark blue, Hominidae other than human are light blue, Cercopithecidae are purple the Hylobatidae are green and the Callitrichidae are yellow. Primate species names are abbreviated as detailed in Materials and Methods, mouse genes are in lower case. Branches labelled with letters show significant (P < 0.0001) evidence of positive selection (see Figure 3 and Additional Files 3 and 4 details) and asterisks indicate branches showing significant (P < 0.0001) evidence for negative selection.