Phylogenetic tree of Aurora-A, Aurora-B, and Aurora-C kinases rooted by PLK4 kinases. Major organism groups (with colours, fonts) are mammals (red, bold italic), cold-blooded vertebrates (deep blue, italic), urochordates (orange, italic), invertebrates, (purple, italic), plants (green, italic), fungi (black, italic) and protists (light blue, italic). "Original" indicates the first Aurora identified from Drosophila melanogaster . Plant sequences are identified by their Genbank accession number. Stacks of numbers show, in descending order, the percent occurrence of nodes in greater than 50% of 1000 bootstrap replicates of neighbor joining (plain text) and maximum parsimony (italicized text) analyses or greater than 50% of 10000 quartet puzzling steps of maximum likelihood analysis (in curved parentheses) or Bayesian posterior probability (only 0.90 or greater, in square parentheses). Asterisks ("*") indicate those nodes supported 70% or greater by the first three tree-building methods and 0.90 Bayesian posterior probability. Nodes with one or two values less than 50% have dashes ("-") while values less than 50% are unmarked. Scale bar represents 0.1 expected amino acid residue substitutions per site.