Skip to main content

Table 1 Profile of the 28 SNPs

From: Evidence of recent natural selection on the Southeast Asian deletion (--SEA) causing α-thalassemia in South China

     Derived-allele frequency P value for HWE test in CRS(Nc = 149)
No. SNP ID Positiona Polymorphismb Carrier (Nc = 76) Normal (Nc = 138)  
1 rs2541593 43423 A/C 0.217 0.362 0.858
2 rs216606 57194 G/A 0.072 0.087 0.533
3 rs3785288 67230 T/C 0.138 0.261 0.849
4 rs2541622 76258 G/A 0.138 0.268 0.981
5 rs216091 97141 G/A 0.125 0.214 0.050e
6 rs2238368 110328 C/T 0.138 0.279 0.908
7 rs2562164 116743 G/A 0.289 0.529 0.112
8 rs2562185 132314 G/A 0.658 0.377 0.328
9 rs77308790d 135020 C/T 0.493 0.091 0.180
10 rs6600143 141389 A/C 0.132 0.264 0.605
11 rs2858925 148039 C/G 0.645 0.341 0.198
12 rs3760053d 151243 T/G 0.520 0.098 0.319
13 rs1211375 180281 C/A 0.757 0.482 0.774
14 rs3918352 187889 A/G 0.158 0.348 0.949
15 rs1203974 217459 A/G 0.704 0.464 0.541
16 rs11248914 233563 C/T 0.243 0.388 0.909
17 rs2252214 237751 C/T 0.171 0.341 0.662
18 rs4374177 246244 A/G 0.171 0.355 0.764
19 rs2239739 251854 A/G 0.730 0.457 0.918
20 rs9940585 262935 T/C 0.632 0.308 0.417
21 rs2685126 264053 G/A 0.211 0.319 0.967
22 rs214247 289222 T/C 0.066 0.163 0.166
23 rs1981492 296690 G/A 0.112 0.236 0.996
24 rs11648673 317795 G/A 0.053 0.127 0.155
25 rs1573733 363556 G/A 0.546 0.290 0.309
26 rs4984666 386363 A/C 0.224 0.420 0.409
27 rs1698232 425556 T/C 0.184 0.377 0.379
28 rs3785301 456923 G/T 0.717 0.551 0.426
  1. a Positions in chromosome 16 are based on NCBI, build 36.3.
  2. b Alleles on the positive strand; ancestral state is named first.
  3. c Number of individuals.
  4. d These two SNPs indicate a hitchhiking effect.
  5. e P < 0.05 in the Hardy-Weinberg equilibrium test.