Figure 3

Conserved linkage of PPP1R2P1 and PPP1R2P3. PPP1R2P1 and PPP1R2P3 location in terms of chromosome and flanking genes is presented concerning each species where were found, showing the conserved linkage. Divergence time is shown on the left. The nucleotide number flanking the pseudogenes is related to the parental PPP1R2 message. Black boxes refer to the short interspersed elements (SINEs) Alu repeats that are primate-specific. Grey boxes refer to the long interspersed elements (LINEs), in this case a LINE1 element. Number above the boxes indicates the location where the repeat interrupted the sequence. In the case of chimpanzee PPP1R2P1, a duplicated pseudogene was originated and the repeats are located in the middle of both, and so, the numbers refer to the final of one pseudogene and the beginning of the other. Also, a deletion is shown (129 to 194) that is common to all pseudogenes with the exception of gibbon and marmoset and a deletion (3186 to 3295) also occurred in rhesus monkey. TAP1: transporter 1, ATP-binding cassette, sub-family B; HLA-DMB: major histocompatibility complex, class II, DM beta; SGCD: sarcoglycan delta; TIMD4: T-cell immunoglobulin and mucin domain containing 4.