Molecular adaptation of a plant-bacterium outer membrane protease towards plague virulence factor Pla

Table 2 Molecular environment of the substituted sites in Pla structure and Epo model

	Pla	Contact	Epo	Contact
MRKX05	K161	solvent	N159	Q160, R161
	G162	-	Q160	N159, R161
	V163	p160, m210	R161	N159, Q160, p158
	R164	y209, t142	P162	R161
	V165	H101, a143, g145, i166	G163	-
MRKX10	K262	e207, t214	T260	S210, t212, d259
	N263	D212, d261	I261	d259
	V268	I270	A266	i257
	s269	q258	s267	q256
	I270	t257, V268, a274	L268	-
	G271	-	D269	a32, g270

Residues whose side chains come within 4 Å of the central amino acid are listed. The amino acids in each loop are indicated in different font styles, L3 (G145-V165) in bold, L4 (H208-L213) underlined and L5 (G255-A274) in italics in Pla numbering.
Residues that are conserved at the site are shown in lower case letters, and the non-conserved ones in capital letters.

ISSN: 2730-7182