Figure 1From: Phylogenomics of phosphoinositide lipid kinases: perspectives on the evolution of second messenger signaling and drug discoveryGeneral pathway for phosphatidylinositide (PI) synthesis. Major PI types with phosphorylation sites labeled (3,4,5 in red) are shown along with the phophorylation and dephosphorylation reactions catalyzed by different phosphoinositide kinase (PIK) types and phosphatases, respectively. Figure partially adapted from Figure 1 of Weernink et al. [6].Back to article page