Figure 1

SNP assessment on lower coverage. Paired comparisons between E. coli strains and K12 strain as reference genome. We used two set of E. coli strains: Complete genomes obtained from Sanger reads (green box) and Sanger reads simulated from complete genomes with coverage approximate of 1X (yellow box). For each alignment, we determined the percentage of SNPs by gene fragment (SNP number/length of contig; Y axis) by our methodology. Boxes inside the graphic include the median values (middle line) and the first and third quartiles (lower and upper lines) of the distribution. Abscissa: E. coli strains.