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Table 2 Indices of diversity and selection at the ELA-DRA and DQA

From: Adaptive molecular evolution of the Major Histocompatibility Complex genes, DRA and DQA, in the genus Equus

 

Length (bp)

N

A

PIP/VNP

R

K2P distance (%)

AA distance (%)

d N

d S

dN/dS

DRA

243

33

22

9/15

4.75

1.3(0.4)

1.7 (0.7)

0.008 (0.003)

0.025 (0.011)

0.32

DQA

201

55

48*

70/96

1.34

13.7(2.2)

21.6 (4.4)

0.105 (0.019)

0.106 (0.021)

0.99

  1. Length = number of base pairs (bp); N = number of alleles when considering identical alleles across taxa separately; A = number of alleles across taxa; PIP = parsimony informative positions; VNP = variable nucleotide positions; R = transition/transversion bias; K2P distance = average mean evolutionary distance determined using the Kimura 2-parameter gamma model (K2P+Γ); AA = average mean poisson-corrected amino acid distance; dS = synonymous base pair substitution rate; dN = non-synonymous base pair substitution rate; Standard errors of estimates are shown in parentheses. *Includes the allele Eqbu-DQA*21, with a stop codon, while all other estimates exclude it.