| |
MKKS
|
BBS10
|
BBS12
|
CCT8L1
|
|---|
|
No. species2
|
14
|
11
|
11
|
5
|
|---|
|
Size (W
B
)3
|
5.7770
|
4.6020
|
5.8949
|
3.3859
|
|
B-index (B
B
)4
|
0.6976
|
1.1079
|
1.0284
|
0.3196
|
|
Unbiased pair-wise distance (B
B
× 2)
|
1.3952
|
2.2159
|
2.0568
|
0.6393
|
|
L
B
(B
B
× W
B
)5
|
4.0300
|
5.0987
|
6.0623
|
1.0822
|
|
Average D
ij
(D
B
)6
|
2.0951
|
2.9660
|
3.2858
|
0.8017
|
|
CCT8
7
| | | | |
|
Size (W
C
)
|
5.5202
|
4.5503
|
4.3647
|
3.1100
|
|
B-index (B
C
)
|
0.1146
|
0.1373
|
0.0992
|
0.0227
|
|
Unbiased pair-wise distance (B
C
× 2)
|
0.2291
|
0.2747
|
0.1983
|
0.0454
|
|
L
C
(B
C
× W
C
)
|
0.6324
|
0.6250
|
0.4328
|
0.0706
|
|
Average D
ij
(D
C
)
|
0.3394
|
0.3687
|
0.2709
|
0.0545
|
|
B
B
/B
C
|
6.0873
|
8.0692
|
10.3669
|
14.0793
|
|
L
B
/L
C
|
6.3725
|
8.1579
|
14.0072
|
15.3286
|
|
D
B
/D
C
|
6.1730
|
8.0445
|
12.1292
|
14.7101
|
|
W
B
/W
C
|
1.0465
|
1.0114
|
1.3506
|
1.0887
|
- 1Only the human CCT8L2 branch was included in the tree. The CCT8L1 branch had equivalent length; 2Chaperonin-BBS sequences used in the trees were from the following species (see the legend for Figure 2 for a complete list of abbreviations and species names). MKKS: Bt, Cf, Dr, Ec, Ga, Gg, Hs, Md, Mm, Mmu, Ol, Rn, Tr, Xt; BBS10: Bt, Cf, Dr, Ec, Ga, Hs, Md, Mm, Ol, Rn, Tr; BBS12: Bt, Cf, Dr, Ec, Ga, Gg, Hs, Mm, Ol, Rn, Tr, Xl; CCT8L: Bt, Cf, Hs, Mm, Rn. 3Size is the average number of sequences contained in a cluster over evolutionary time (see Methods); 4The B-index measures the average substitutions per site (evolutionary distance) of the sequences within a cluster from their common ancestor; 5L is the length of the tree (sum of the lengths of all branches); 6Average D
ij
is the average pair-wise evolutionary distance of the sequences; 7Estimates for CCT8 were computed over corresponding species represented by the sets of MKKS, BBS10, BBS12 or CCT8L proteins (see footnote 2, above).
