Figure 6

Type-1 B1 isoform-specific region. The type-1 B1 isoform-specific region contains three conserved microdomains. (A) Schematic representation of the type-1 B1 isoform-specific regions. Positions of the S-rich motif, the SP residues, and the DL-rich motif are indicated by colored boxes. (B) The alignment and Sequence Logo representation of the conserved microdomains found in the type-1 B1 isoform-specific region. The amino acid residues are represented in the default color scheme of ClustalX. Asterisks indicate identical residues and colons indicate similar residues. (C) The N-terminal region of Brugia malayi EcR contained the S-rich motif-like sequence (modified S-rich motif) and the DL-rich motif. Positions of the modified S-rich motif and the DL-rich motif are indicated in the schematic representation of the N-terminal region of B. malayi EcR (amino acid residues 1-151). The alignment of the microdomains found in B. malayi with their corresponding microdomains in the type-1 B1 isoform-specific region reveals their sequence similarity. The amino acid residues are represented in the default color scheme of ClustalX. Asterisks indicate identical residues and colons indicate similar residues.