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Figure 5 | BMC Evolutionary Biology

Figure 5

From: The evolutionary trajectory of mitochondrial carrier family during metazoan evolution

Figure 5

The amino acid's spatial positioning and its evolutionary analysis in TR DOWN . (A) ADP/ATP carrier viewed from the cytosol. The surf region represents TRDOWN. Red indicates hydrophobic residues. Blue indicates hydrophilic residues. Green indicates other residues. (B) The ADP/ATP carrier viewed from the matrix. Geno3D was used in the homology modelling of protein [61]. All the protein structures including the following structure were drawn by VMD [62]. (C) The logo chart of sequences in TRDOWN135 from vertebrates. (D) The logo chart of sequences in TRDOWN246 from vertebrates. (E) The logo chart of sequences in TRDOWN135 from invertebrates. (F) The logo chart of sequences in TRDOWN246 from invertebrates. Red indicates hydrophobic residues, blue indicates hydrophilic residues, and black indicates other residues. The logo chart describes the residue changes in the same vertical plane according to the space structure orientation of TRDOWN for metazoan evolution. WebLogo was applied into the logo analysis [21]. Ver indicates vertebrates, while Non-ver indicates invertebrates.

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