| Dysferlin | Paralogs | Orthologs |
---|
C2A | No | N/A | N/A |
C2B | No | N/A | N/A |
C2C | Yes | No | No |
C2D | Yes | No | Yes (1,2) |
C2E | Yes | Yes | Yes (1) |
C2F | Yes | Yes | Yes(1) |
- Key: Yes indicates that all five aspartates are conserved; No indicates all five could not be identified; N/A indicates these domains were not tested for aspartates as the corresponding dysferlin C2 domains have not conserved the five aspartates; 1 indicates no conservation in Cele; 2 indicates no conservation in Dmel. Residues considered as having potential for calcium coordination include aspartic and glutamic acid.