Ancient lineages of the keratin-associated protein (KRTAP) genes and their co-option in the evolution of the hair follicle

Table 2 Expect values from blasts using chicken-expressed krtap sequences

Results of BLAST searches with KRTAP proteins of G. gallus run against H Sapiens genome
Chicken gene providing expressed sequence	KRTAP sequences in top 1000 hits	Top BLAST hit in H sapiens	Its Expect value in a BLAST 2- sequences analysis	Uniprot ID of orthologous protein in H sapiens	Its Expect value in a BLAST 2- sequences analysis	Expressed in
KRTAP10-4	98	KRTAP5-7	0.054	P60372	0.031	Kidney
KRTAP 5–1-like	87	KRTAP9-1	0.038	Q6L8H4	0.31	Kidney
KRTAP 9–1-like	86	KRTAP 9–1	0.30	A8MXZ3	0.32	Colon
KRTAP21-1-like	17	KRTAP 6–3	0.019	Q3LI58	12	Kidney
KRTAP 10–4 (2^nd example)	87	KRTAP 9–1	5 × 10^–4	P60372	13	Kidney

Expression data for Gallus gallus were downloaded from bgee.org, and included the following data sets: GSE30352, GSE41338, GSE41637, SRP057141, SRP092128, and SRP097223. Unique identifiers (ENSGALGx) for genes encoding KRTAP-like proteins were found by querying the Ensembl genome annotation for Gallus gallus (Genome version GRCg7b). A gene was flagged as “expressed” if it had at least 2 read counts in an RNAseq experiment

ISSN: 2730-7182