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Table 1 Positive selection tests in nine IRFs genes and the Val129 site of human IRF9 detected to be under positive selection by the Branch-site model in PAML

From: Positive selection-driven fixation of a hominin-specific amino acid mutation related to dephosphorylation in IRF9

Gene

Gene Ensembl ID

p-value

AAlen

GC(%)

IRF1

ENSG00000125347

0.998

325

54.60%

IRF2

ENSG00000168310

0.995

349

50.67%

IRF3

ENSG00000126456

1.000

427

62.25%

IRF4

ENSG00000137265

0.448

451

57.74%

IRF5

ENSG00000128604

0.469

514

61.10%

IRF6

ENSG00000117595

0.996

467

53.92%

IRF7

ENSG00000185507

1.000

503

68.28%

IRF8

ENSG00000140968

1.000

426

58.24%

IRF9

ENSG00000213928

0.004

393

58.46%

PSS

Location in genome

Codon

V129

chr14:24,163,398–24,163,400

GTA

  1. The p-values were estimated with the χ2 test. PSS indicates the positively selected site. AAlen and GC(%) indicate the longest length of isoforms and GC content of the human IRF9, respectively